Rob Galbraith’s Digital Photography Insights has a great article about National Geographic’s first cover story shot entirely in digital. (Props to Haberlach for the link.)
Digital had many of the advantages I’d expect: less equipment to get lost, easy backups, ability to review pictures on-site, and easier remote collaborative editing. The disadvantages were more surprising to me, and included having to deal with brightness differences on different screens, inability to edit on a large horizontal surface like a light-table, and poor contrast compared to slides when showing photos to a large group.